Evaluation of Active Coagulation Time in Stray Dogs in Kabul City

Fazalwali Jalalzai; Nasrin  Stanikzai; Kifayat Ullah  Sadat; Nageebullah  Zafari

doi:10.62810/jnsr.v4i2.204

Authors

Fazalwali Jalalzai Kabul University, Department of Para-clinic, Faculty of Veterinary Science, Jamal Mina, Kabul, Afghanistan https://orcid.org/0009-0004-6709-6008
Nasrin Stanikzai Kabul University, Department of pre-clinic, Faculty of Veterinary Science, Jamal Mina, Kabul, Afghanistan
Kifayat Ullah Sadat Kabul University, Department of Animal production and Management, Faculty of Veterinary Science, Kabul, Afghanistan https://orcid.org/0009-0001-9071-3885
Nageebullah Zafari Kunduz University, Department of Pre-clinic, Faculty of Veterinary Science, Kunduz -Afghanistan

DOI:

https://doi.org/10.62810/jnsr.v4i2.204

Keywords:

Coagulation, pathogen, platelets, Castration

Abstract

Blood coagulation is a vital physiological process in animals, and any disturbance in this system may lead to serious clinical complications. It is a simple screening test used to assess hemostasis. This study aims to determine the Active Coagulation Time (ACT) in stray dogs in Kabul City and to compare the mean value with those reported in previous studies. This descriptive cross-sectional study was conducted from September 1 to September 15, 2020, at the Mayhew Clinic in Kabul City. A total of 40 clinically healthy stray dogs were included in this study. For ACT measurement, 2–3 drops of blood were collected from the cephalic vein and placed on a clean glass slide. The first fibrin strand was checked every 10–15 seconds. Data were analysed using correlation analysis and a one-sample t-test. The mean Active Coagulation Time was 159.85 ± 33.81 seconds. Age and sex had no statistically significant effect on ACT (p > 0.05). However, the one-sample t-test demonstrated a statistically significant difference between the mean ACT observed in this study and values reported in previous studies (p < 0.001). The ACT values in stray dogs in Kabul City differ significantly from those reported in earlier studies. Despite its limitations, the ACT is a practical and useful screening method for the preliminary assessment of blood coagulation in resource-limited settings, and its use before surgical interventions is recommended.

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